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KMID : 0360220130540020289
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Journal of the Korean Ophthalmological Society
2013 Volume.54 No. 2 p.289 ~ p.295
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Age-Related Differences of Spectral-Domain Optical Coherence Tomography Data in Koreans
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Suh Ji-Young
Seo Hong-Ryung
Rho Sae-Heun
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Abstract
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Purpose: We evaluated the thickness of RNFL and optic nerve head parameters with age in normal eyes using Spectral-Domain Optical Coherence Tomography (SD-OCT). Methods: A total of 128 normal Korean volunteers in different age groups were recruited (age range, 20-70 years). Results: A significant negative correlation in average RNFL thickness with increasing age was found. The inferior areas (130.31 ± 3.33 μm) were significantly thicker than other areas (superior area 119.05 ± 2.12 μm, nasal area 71.80 ± 0.57 μm, temporal area 77.72 ± 0.16 μm). The average C/D ratios (mean 0.38 ± 0.14) and vertical C/D ratios (mean 0.35 ± 0.11) both showed significant increases with age, and the vertical C/D ratio correlation coefficient was higher (average C/D ratio r = 0.249, vertical C/D ratio r = 0.537). However, rim area, disc area, and cup volume were not correlated with age. Conclusions: From these findings, we conclude that, in normal Koreans, the mean RNFL thickness decreases and the C/D ratio increases with age, with the increase in the vertical C/D ratio being greater.
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KEYWORD
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Optic disc parameter, Retinal nerve fiber layer thickness, Spectral-domain optical coherence tomography
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